Drug Discovery: A Non-Expiring Process
1. Drug Discovery: A Non-Expiring Process

Mahmoud Mirzaei

Volume 2, Issue 2 , Spring 2020, , Pages 46-47

http://dx.doi.org/10.33945/SAMI/AJCB.2020.2.1

Abstract
  Drug is ”a substance used as a medication or in the preparation of medication” [Merriam-Webster Dictionary]. So many natural and synthetic chemical compounds have been examined ...  Read More
Favipiravir: Structural Analysis and Activity against COVID-19
2. Favipiravir: Structural Analysis and Activity against COVID-19

Kun Harismah; Mahmoud Mirzaei

Volume 2, Issue 2 , Spring 2020, , Pages 55-60

http://dx.doi.org/10.33945/SAMI/AJCB.2020.2.3

Abstract
  Within this work, we have performed an in silico research for structural analysis of Favipiravir and its activity against COVID-19. To this aim, tautomers formations of Favipiravir ...  Read More
Lab-in-Silico Insights
3. Lab-in-Silico Insights

Mahmoud Mirzaei

Volume 2, Issue 1 , Winter 2020, , Pages 1-2

http://dx.doi.org/10.33945/SAMI/AJCB.2020.1.1

Abstract
  Recent developments in computer hardware and software, in addition to modern algorithms, have led to new era of scientific laboratories; called Lab-in-Silico. The simulation protocols ...  Read More
Computational Studies of Furanone and its 5Methyl/5Phenyl Derivatives
4. Computational Studies of Furanone and its 5Methyl/5Phenyl Derivatives

Nikoo Ghanbari; Homa Azizian; Mahmoud Mirzaei

Volume 2, Issue 1 , Winter 2020, , Pages 33-38

http://dx.doi.org/10.33945/SAMI/AJCB.2020.1.6

Abstract
  The properties for 2(5H)-furanone and 2(5Methyl)- and 2(5Phenyl)-furanone derivatives have been explored by computational chemistry approach. The subatomic unit calculations have been ...  Read More
Non-Covalent Interactions of N-(4-CarboxyPhenyl)Phthalimide with CNTs
5. Non-Covalent Interactions of N-(4-CarboxyPhenyl)Phthalimide with CNTs

Mehrnoush Molaeian; Asghar Davood; Mahmoud Mirzaei

Volume 2, Issue 1 , Winter 2020, , Pages 39-45

http://dx.doi.org/10.33945/SAMI/AJCB.2020.1.7

Abstract
  Non-covalent interactions of N-(4-carboxyphenyl)phthalimide (CPP) with carbon nanotubes (CNTs) have been investigated to see the effects of interactions on the properties of CPP, which ...  Read More
Antidepressant Activity of Curcumin by Monoamine Oxidase–A Inhibition
6. Antidepressant Activity of Curcumin by Monoamine Oxidase–A Inhibition

Hamidreza Nazemi; Mahmoud Mirzaei; Elham Jafari

Volume 1, Issue 1 , Autumn 2019, , Pages 3-9

http://dx.doi.org/10.33945/SAMI/AJCB.2019.1.2

Abstract
  Antidepressant activity of curcumin (Cur), as a very well–known herbal product, has been investigated within this work. Two tautomeric forms of Cur–a and Cur–b in ...  Read More
Alkali Metal Chelation by 3–Hydroxy–4–Pyridinone
7. Alkali Metal Chelation by 3–Hydroxy–4–Pyridinone

O. Murat Ozkendir; Mahmoud Mirzaei

Volume 1, Issue 1 , Autumn 2019, , Pages 10-16

http://dx.doi.org/10.33945/SAMI/AJCB.2019.1.3

Abstract
  Chelations of neutral and one–electron positive ionic alkali metals including Lithium (Li/Li+), Sodium (Na/Na+) and Potassium (K/K+) by 3–Hydroxy–4–Pyridinone ...  Read More
Flavonoid Derivatives for Monoamine Oxidase–A Inhibition
8. Flavonoid Derivatives for Monoamine Oxidase–A Inhibition

Arman N. Esfahani; Mahmoud Mirzaei

Volume 1, Issue 1 , Autumn 2019, , Pages 17-22

http://dx.doi.org/10.33945/SAMI/AJCB.2019.1.4

Abstract
  The in silico molecular docking (MD) simulations have been performed to examine the efficacy of three flavonoid ligands including chrysin, apigenin and luteolin on monoamine oxidase–A ...  Read More
Comparative Examination of Moclobemide, Tranylcypromine, Phenelzine and Isocarboxazid for Monoamine Oxidase–A Inhibition
9. Comparative Examination of Moclobemide, Tranylcypromine, Phenelzine and Isocarboxazid for Monoamine Oxidase–A Inhibition

Zahra S. Alidoosti; Mahmoud Mirzaei

Volume 1, Issue 1 , Autumn 2019, , Pages 23-28

http://dx.doi.org/10.33945/SAMI/AJCB.2019.1.5

Abstract
  The ligand–receptor complex formations between the monoamine oxidase–A (MAO–A) enzyme and its known inhibitors have been examined based on the in silico approach. ...  Read More