Document Type: Review Article


Department of Chemical Engineering, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran



Natural gas hydrate is a solid crystalline compound formed from the composition of water and gas and is part of the clathrate family. Gas hydrate can be formed by pure gas or a gas mixture consisting of two or more components. Gas hydrates are recognized as non-stoichiometric solids. One of the methods or methods that has been most successful in predicting or recognizing hydrate phases in hydrocarbon equilibrium is based on the relative Kvs size of the vapor-solid equilibrium constant. Tables of equilibrium for species or constituents of hydrates known as normal butane are listed in various articles and books. With the discovery of the heaviest constituents of hydrates, their equilibrium constants need to be more accurately predicted in the un-hydrated phase of the hydrocarbon mixtures, especially in the reservoir fluids.

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[1]      J. Mashhadizadeh, A. Bozorgian, and A. Azimi, Investigation of the kinetics of formation of Clatrit-like dual hydrates TBAC in the presence of CTAB. Eurasian Chemical Communications, 2 (2020) 536-547.

[2]      A. Bozorgian, Z. Arab Aboosadi, A. Mohammadi, B. Honarvar and A. Azimi, Optimization of determination of CO2 gas hydrates surface tension in the presence of non-ionic surfactants and TBAC. Eurasian Chemical Communications, 2 (2020) 420-426.

[3]      S. Zarinabadi, A. Samimi, Problems of hydrate formation in oil and gas pipes deal. Australian journal of basic and applied science, 5 (2011) 741-745.

[4]      A. Bozorgian, Z. Arab Aboosadi, A. Mohammadi, B. Honarvar and A. Azimi, Prediction of Gas Hydrate Formation in Industries. Progress in Chemical and Biochemical Research, 3 (2020) 31-38.

[5]      A. Samimi, Preventing Hydrate Formation in Gas Transporting Pipe Lines with Synthetic Inhibitors. International Journal of science and investigations, 2 (2012) 48-50.

[6]      A.H. Tarighaleslami, A. Bozorgian and B. Raei, Application of the exergy analysis in the petroleum refining processes optimization. In The 1st Territorial Chemistry and Industry Symposium. Lecture number: E-1097, Damghan, Iran (in Persian), (2009).

[7]      A. Samimi, S. Zarinabadi, AHS. Kootenaei, A. Azimi, M. Mirzaei,  Use of data mining in the corrosion classification of pipelines in catalytic reforming units (CRU), Iranian Chemical Communication 7 (2019) 681-691.

[8]      N. Farhami and A. Bozorgian, Factors affecting selection of tubes of heat exchanger. In Int. Conf. on Chem. and Chem. Process IPCBEE, 10 (2011) 223-228.

[9]      D. Mohammadnazar, A. Samimi, Nessacities of Studying HSE Management Position and Role in Iran Oil Industry, Journal of Chemical Reviews, 1 (2019) 252-259.

[10]  B. Raei, A. Ghadi and A. Bozorgian, Heat Integration of heat exchangers network using pinch technology. In 19th International Congress of Chemical and Process Engineering CHISA, (2010).

[11]  C. X. Su, J. F. Mouscadet, C. C. Chiang, H. J. Tsai and L. Y. Hsu, HIV-1 integrase inhibition of biscoumarin analogues. Chem. Pharm. Bull., 54 (2006) 682-686.

[12]  A. Samimi, S. Zarinabadi, A. Bozorgian, A. Amosoltani, T. Esfahani, M. Sadegh and K. Kavousi, Advances of Membrane Technology in Acid Gas Removal in Industries. Progress in Chemical and Biochemical Research, 3 (2020) 46-54.

[13]  A. Lacy and R. O’Kennedy, Studies on coumarins and coumarin-related compounds to determine their therapeutic role in the treatment of cancer. Current Pharm. Design., 10 (2004) 3797-3811.

[14]  A. Bozorgian, The Production of Clay Nano-Composite Epoxy and Comparison of Its Properties with Epoxy Resins. Polymer, 2(2012) 12923-12929.

[15]  M. I. Choudhary, N. Fatima, K. M. Khan, S. Jalil, S. Iqbal and Atta-ur-Rahman, New biscoumarin derivatives-cytotoxicity and enzyme inhibitory activities. Bioorg. Med. Chem., 14 (2006) 8066-8072.

[16]  S.V. Mousavi, A. Bozorgian, N.  Mokhtari, M.A.  Gabris, H.R.  Nodeh, and W.A.W Ibrahim, A novel cyanopropylsilane-functionalized titanium oxide magnetic nanoparticle for the adsorption of nickel and lead ions from industrial wastewater: Equilibrium, kinetic and thermodynamic studies. Microchemical Journal, 145(2019) 914-920.

[17]  U. M. Lindstrom, Stereoselective organic reactions in water. Chem. Rev. 102 (2002) 2751-2772.

[18]  A. Bozorgian, N.M. Nasab, and H. Mirzazadeh, Overall effect of nano clay on the physical mechanical properties of epoxy resin. World Academy of Science, Engineering and Technology International Journal of Materials and Metallurgical Engineering, 5 (2011) 21-24.

[19]  S. Chitra, N. Paul, S. Muthusubramanian and P. Manisankar, A facile, water mediated, microwave-assisted synthesis of 4,6-diaryl-2,3,3a,4-tetrahydro-1H-pyrido[3,2,1-jk] carbazoles by a domino Fischer indole reaction–intramolecular cyclization sequence. Green Chem. 13 (2011) 2777-2785.

[20]  K. Kavousi, S. Zarinabadi and A. Bozorgian, Optimization of the Gasoline Production Plant in order to Increase Feed. Progress in Chemical and Biochemical Research, 3 (2020) 7-19.

[21]  A. Pourabadeh, B. Nasrollahzadeh, R. Razavi, A.  Bozorgian and M. Najafi, Oxidation of FO and N 2 Molecules on the Surfaces of Metal-Adopted Boron Nitride Nanostructures as Efficient Catalysts. Journal of Structural Chemistry, 59(2018) 1484-1491.

[22]  A. Bozorgian and M. Ghazinezhad, A Case Study on Causes of Scale Formation-Induced Damage in Boiler Tubes. J Biochem Tech Special Issue, 2((2018) 149-153.

[23]  M. K. Mohammadi, S. J. Saghanezhad and N. Razzaghi-asl, Efficient and convenient oxidation of benzyl halides to carbonyl compounds with Sodium nitrate and Acetic acid by phase transfer catalysis in aqueous media. Bull. Chem. Soc. Ethiop., 31 (2017) 535-544.

[24]  A. Bozorgian, P. Khadiv Parsi, M.A. Mousavian, experimental study of simultaneous effect of surfactant and salt on drop-interface coalescence, shimi & mohandesi shimi iran (persian), 27(2009) 59-68.






Bozorgian, A., Investigation of Predictive Methods of Gas Hydrate Formation in Natural Gas Transmission Pipelines, Ad. J. Chem. B, 2 (2020) 91-101

DOI: 10.33945/SAMI/AJCB.2020.3.1