Document Type : Original Research Article
1 Student at Dalian Medical University, Dalian, Liaoning, China
2 Student at Huazhong University of Science and Technology (HUST), Wuhan, China
3 3Bachelor of Dental Surgery student at Dalian Medical University, Dalian, China
This article compares the effects of pre- and post-transplant diabetes on the complications and consequences of kidney transplantation. This study was performed in Rasht city on patients who received a kidney transplant annually in 2019-2020. This study was performed by historical cohort method. Patients were divided into three groups that were compatible in terms of age, sex, and type of underlying renal disease. The first group consisted of patients who had diabetes before transplantation. The second group consisted of patients who did not have diabetes before transplantation but developed diabetes afterwards. The third group consisted of patients who did not have diabetes before or after transplantation. Record of all patients for one year in terms of function, delay and rejection of kidney transplantation, systemic infection, cancer, recurrence of underlying kidney disease, cardiovascular diseases, and their deaths are being investigated. The total number of patients participating in this study was 155 and their mean ages in the first, second, and third groups were 47, 47.1, and 47.3 years old, respectively. The incidence of the mentioned consequences and complications in each group 82.9, 57.1, and 97.1, respectively, was a percentage. After one year, the retention rate of transplanted kidney was 68.5, 77.1, and 47.1 was a percentage and the survival rate of patients was 82.8, 88.5, and 97.1 was a percentage, respectively. In this study, 21% of PTDM was obtained up to one year after kidney transplantation.
- M. Danovitch. Hand book of kidney transplantation. 4 ed. Philadelphia: Lippincott Williams& Wilkins, 2005.
- E. Joist, D.C. Brennan. Post-transplant diabetes mellitus in renal transplant recipients. 2006.
- Gunnarsson, P. Amer, G. Lundgren, G. Magnusson, J. Ostman, C.G. Groth. Diabetes mellitus-a more- common-than-believed complication of renal transpläntation. Trunsplant Proc., 11(2) (1979) 1280-1.
- L. Kasiske, J.J. Snyder, D. Gilbertson, Matas Al Dibetes mellitus after kidney transplantation in the United States. Am J Transplant., 3(2) (2003) 178-85
- G. Cosio, T.E. Pesavento, K. Osei, M.L. Henry, R.M. Ferguson. Post-transplant diabetes mellitus: increasing incidence in renal allograft recipients transplanted in recent years. Kidney Int, 59(2) (2001) 732-7.
- I. Mabudian, J. Thomson, P. Kamar. Immunological and non-immunologic association post transplant dhabetes mellitus (PTDM). J Allerg clin Immun., 113 (2Suppl ()1216-9.
- Rodrigo, G. Fer nández-Fresnedo, R. Valero, J.C. Ruiz, C. Piñera, R. Palomar, et al. New onset diabetes after kidney transplantation: risk factors. J Am Soc Nephrol., 17(12 Suppl3) (2006) S291-5.
- G. Cosio, L.J. Hickson, M.D. Gritfin, M.D. Stegall, Y. Kudva. Patient survival and cardiovascular risk after kidney transplantation the challenge of diabetes. Am J Transplant, 8(3) (2008)593-9.
- Fernández-Fresnedo, R Escallada, AL de Francisco, E Rodrigo, JA Zubimendi, JC Ruiz, et al. Post trunsplant dinbetes is a cardiovascular nisk fuctor in renal transplant patients. Transplant Proc, 35(2) (2003) 700- 6.
- Ducloux, A. Kazory, J.M. Chalopin. Post transplant diabetes mellitus and atherosclerotic events in renal transplant recipients. A prospective study. Transplantation., 79(4) (2005) 438-43.
- Lentine, D. Brennan, M. Schnitzler. Incidence and prediction of myocardinal infarction after kidney transplantation. J Am Soc Nephrot., 16(2) (2005) 496-506.
- A. Friedman, T.P. Shyh, M.M. Beyer, T. Manis, K.M. Butt. Post tranısplant diabetes in kidney transplant recipients, Am J Nephrol., 5(3) (1985) 196-202.
- P. Boudreaux, L. McHugh, D.M. Canafax, N. Ascher, D.E. Sutherland, W. Payne, et al. The impact of cyclosporine and combination immunosuppression on the incidence of post-transplant diabetes in rens allograft recipients. Transplantation., 44 (3) (1987) 376-8I.
- M. Miles, N. Sumrani, R. Horowitz, P. Homel, V. Maursky, M.S. Markell, et al. Diabetes mellitus after ret transplantation: as deleterious as non-transplant-associated diabetes?? Transplantation, 65(3)(1998) 380-4.
- Vesco, M. Busson, J. Bedrossian, M.O. Bitker, C. Hiesse, P. Lang. Diabetes mellitus after renal transplantation: characteristics, outcome and risk factors. Transplantation., 61(10) (1996)1475-8.
- K. Revanur, A.G. Jardine, D.B. Kingsmore, B.C. Jaques, D.H. Hamilton, R.M. Jmdal. Influence of diabetes mellitus on patient and graft survival in reciptents of kidney transplantatim. Clin Transplant., 15(2) (2001) 89. 94
- M. Jindal, Hjelmesaeth. Impact and management of post transplant diabetes mellitus. Transplantation, 70(11 Suppl) (2000) S58-63.
- G. Cosio, Y. Kudva, M. van der Velde, T.S. Larson, S.C. Textor, M.D. Giniffin, et al. New onset hyperglycemia and diabetes are ussociated with increased cardiovascular risk after kidney transplantution. Kidney Int, 67(6) (2005) 2415-21.
- G. Cosio, T.E. Pesavento, S. Kim, K. Osei, M. Henry, R.M. Ferguson. Patient survival after renal transplantation IV Impact of post transplant diabetes Kidney Int, 62(4) (2002) 1440-6
- D. Bloom. Crutchlow MF New-onset diabetes mellitus in the kidney recipient diagnosis and management strategies. Clin J Am Soc Nephrol., 3 Suppl 2 (2008) S 38-48
- T. Mathew, M. Rao, V. Job, S. Ratnaswamy, C.K. Jacob. Post transplant hyperglycemia: a study of risk factors. Nephral Diat Transplant, 18(1) (2003) 164-71.
- Samimi, B. Almasinia, E. Nazem, R. Rezaei, A. Hedayati, M. Afkhami, Investigating MIDEA Corrosion Treatment on Carbonic Simple Steel in Amin Unit of Isfahan Refinery, International Journal of science and investigations, 1 (2012) 49-53
- Samimi, A. Samimi, Explosion of Resources Management in Iran, International Journal of Innovation and Applied Studies, 1 (2012) 232-235