Mehrukh Zehravi; Mudasir Maqbool; Irfat Ara
Abstract
Curcumin is a polyphenol derived from the Curcuma longa plant (diferuloylmethane). For thousands of years it has been employed in Ayurvedic medicine for a range of therapeutic features, ...
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Curcumin is a polyphenol derived from the Curcuma longa plant (diferuloylmethane). For thousands of years it has been employed in Ayurvedic medicine for a range of therapeutic features, including relief of pain, reactive oxygen activity, inflammatory prevention and antibacterial qualities. Curcumin activity is displayed in the cell through a clustering of signaling pathways at different stages. Curcumin's anticancer capabilities have recently been examined in a number of ways, including expression of cancer gene, cancer spread, cell cycle control and regulation, scheduled death of cells and malignancy development. Curcumin's enormous promise as a cancer treatment has been demonstrated in all of such studies. It has many applications in the fight against cardiovascular, reactive oxygen, microbial and fungal diseases. Curcumin nano-formulations are also investigated for its impact on cancer and therapeutic advantages. The current review summarizes the investigations done as well as data supporting the pharmacological activity of curcumin.
