Molecular Docking Study and Insilico Design of Novel Drug Candidates against Salmonella typhi
Molecular Docking Study and Insilico Design of Novel Drug Candidates against Salmonella typhi

John Philip Ameji; Adamu Uzairu; Adamu Gideon Shallangwa; Sani Uba

Volume 4, Issue 4 , December 2022, , Pages 281-298

https://doi.org/10.22034/ajcb.2022.366678.1129

Abstract
  Typhoid fever, a disease caused by a Gram-negative bacterium known as Salmonella typhi constitutes a significant cause of morbidity and mortality, especially in developing nations. ...  Read More
In-Silico Design of Phthalazine Derivatives as VEGFR-2 ‎Inhibitors: Molecular Docking and Pharmacological Profile ‎Studies
In-Silico Design of Phthalazine Derivatives as VEGFR-2 ‎Inhibitors: Molecular Docking and Pharmacological Profile ‎Studies

Sagiru Hamza Abdullahi; Adamu Uzairu; Gideon Adamu Shallangwa; Sani Uba; Abdullahi Bello Umar

Volume 4, Issue 4 , December 2022, , Pages 309-327

https://doi.org/10.22034/ajcb.2022.374266.1135

Abstract
  According to the world health organization (WHO) reports, cancer is thought to be the condition that causes the most fatalities after coronary disease, and by 2030, thirteen million ...  Read More
Phytochemical Screening and Evaluation of the Antioxidant Potentials of the Stem Bark Extracts of Erythrophleum Africanum (African Blackwood)
Phytochemical Screening and Evaluation of the Antioxidant Potentials of the Stem Bark Extracts of Erythrophleum Africanum (African Blackwood)

Abdulrazaq Tukur; Nasiru Malan Musa; Tajuddeen Jimoh Abdullahi; Murtala Yusuf; Maryam Ismail Usman

Volume 4, Issue 3 , August 2022, , Pages 202-208

https://doi.org/10.22034/ajcb.2022.345261.1123

Abstract
  Antioxidant agents have been reported to play a significant role in protecting against infections induced by oxidant damage. Erythrophleum africanum have been found to be a reservoir ...  Read More
Development of UV Spectrophotometric Method for Quantitative Estimation of Quercetin in Ocular Formulations
Development of UV Spectrophotometric Method for Quantitative Estimation of Quercetin in Ocular Formulations

Rabiah Bashir; Tabasum Ali; Shabnam A Kawoosa; Nisar A Khan

Volume 4, Issue 3 , August 2022, , Pages 222-226

https://doi.org/10.22034/ajcb.2022.339513.1121

Abstract
  To estimate quercetin in ophthalmic formulations, an accurate and simple UV spectroscopic method has been developed. Quercetin shows absorbance maximum at 255 in the ethanol. In the ...  Read More
Evaluation of the Stability of Compound 2-Fluoro-1, 3, 2-Dioxaphosphinane in Axial and Equatorial Conformations by NBO Analysis
Evaluation of the Stability of Compound 2-Fluoro-1, 3, 2-Dioxaphosphinane in Axial and Equatorial Conformations by NBO Analysis

Zahra Mokhayeri

Volume 4, Issue 2 , April 2022, , Pages 104-112

https://doi.org/10.22034/ajcb.2022.329529.1108

Abstract
  Cyclohexane and hetero cyclohexane are good models for studying stereo electronics. The derivatives of 1, 3-dioxane are the good examples of ground and transition states of hyper-conjugated ...  Read More
Isolation and Characterization of Neoduline from the Rhizome of Dolichos pachyrhizus Harm
Isolation and Characterization of Neoduline from the Rhizome of Dolichos pachyrhizus Harm

Nasiru Malan Musa; Oyewale Ojo Adebayo; Muhammad Sani Sallau; Tijjani Ali

Volume 4, Issue 2 , April 2022, , Pages 113-123

https://doi.org/10.22034/ajcb.2022.332067.1113

Abstract
  Dolichos is a genus of twining plants found in both the Northern and Southern hemispheres, with the most frequently grown and used species being Dolichos biflorus and Dolichos lablab. ...  Read More
An Overview of the History of Using Adsorbents in Environment
An Overview of the History of Using Adsorbents in Environment

Andi Johnson; Andi Brous; Amir Samimi

Volume 4, Issue 2 , April 2022, , Pages 124-134

https://doi.org/10.22034/ajcb.2022.335689.1117

Abstract
  There are several techniques for removing contaminants from water and wastewater. In the meantime, the surface adsorption is one of the simplest, the most effective, and economical ...  Read More
Green and Efficient Synthesis of Baclofen
Green and Efficient Synthesis of Baclofen

Pearl Rhea Fernandes; Ashwini . Madnala; Nisha . Donde; Amit Anil Pawar; Maryappa C. Sonawale

Volume 4, Issue 2 , April 2022, , Pages 158-163

https://doi.org/10.22034/ajcb.2022.342298.1120

Abstract
  Baclofen is a Gamma Amino Butyric acid (GABA) agonist to relax skeletal muscles. It is especially effective in treating muscular spasticity. In this research, we now describe the ...  Read More
Phytochemical Screening and the Effect of Methanolic Leaves Extract of Senna mimosoides on Inflammatory Stimulus-Induced Leukocyte Mobilization (In-vivo)
Phytochemical Screening and the Effect of Methanolic Leaves Extract of Senna mimosoides on Inflammatory Stimulus-Induced Leukocyte Mobilization (In-vivo)

Abdulrazaq Tukur; Nasiru Malan Musa; Jimoh Tajuddeen Abdullahi; James D Habila; Martha Bamidele Omotola

Volume 4, Issue 1 , March 2022, , Pages 29-38

https://doi.org/10.22034/ajcb.2022.323175.1105

Abstract
  In traditional medicine, the leaves of Senna mimosoides, has been used to cure oedema and breastfeeding poisoning in newborns. The animal model experiment included a total of twenty-five ...  Read More
Green synthesis of Copper Nanoparticles and Investigation of its Antimicrobial Properties
Green synthesis of Copper Nanoparticles and Investigation of its Antimicrobial Properties

Ifeoluwa Israel Alao; Ifeoluwa Peter Oyekunle; Kingsley O Iwuozor; Ebuka Chizitere Emenike

Volume 4, Issue 1 , March 2022, , Pages 39-52

https://doi.org/10.22034/ajcb.2022.323779.1106

Abstract
  Nanoparticles containing copper metal ions and their derivatives are being used for different medical purposes to prevent infections, ulcers etc. The aim of this study was to qualitatively ...  Read More
A Highly Sensitive Colorimetric Determination of Paraquat by Silver Nanoparticles
A Highly Sensitive Colorimetric Determination of Paraquat by Silver Nanoparticles

Neda koohzadi; Zeinab Rezayati Zad

Volume 3, Issue 4 , December 2021, , Pages 311-322

https://doi.org/10.22034/ajcb.2021.302596.1092

Abstract
  In this work, we describe a simple, selective and sensitive colorimetric method for the detection of Paraquat. In this approach, the synthesized silver nanoparticles (AgNPs) solution ...  Read More
Crystal structure, Hirshfeld surface, Energy framework, and Molecular docking analysis of 4-(methoxyphenyl)acetic acid
Crystal structure, Hirshfeld surface, Energy framework, and Molecular docking analysis of 4-(methoxyphenyl)acetic acid

Ruchika Sharma; Sumati Anthal; Nitin G Ghatpande; Mahidansha M Shaikh; Jagannath S Jadhav; Saminathan Murugavel; Sonachalam Sundramoorthy; RAJNI Kant

Volume 3, Issue 4 , December 2021, , Pages 333-347

https://doi.org/10.22034/ajcb.2021.307316.1097

Abstract
  The crystal structure of (4-methoxyphenyl) acetic acid (C9H10O3) exists in the monoclinic space group P21/c having unit cell parameters: a = 16.268 (15), b = 5.858 (5), c = 9.157 (8) ...  Read More
Determination of Total Phenolic Compounds and Antioxidant Capacity of Rosmarinus officinalis L. via Microwave-Assisted Extraction
Determination of Total Phenolic Compounds and Antioxidant Capacity of Rosmarinus officinalis L. via Microwave-Assisted Extraction

Emel Akbaba; Mehmet Yaman

Volume 3, Issue 4 , December 2021, , Pages 348-360

https://doi.org/10.22034/ajcb.2021.306163.1096

Abstract
  Due to the toxicity of synthetic antioxidants, their application has been limited or even banned in certain countries. The extraction of phenolic compounds and flavonoids from plant ...  Read More
The Contents of some Macro and Trace Elements in Uniflora and Multiflora Honey Samples Collected from Three Regions in East Libya
The Contents of some Macro and Trace Elements in Uniflora and Multiflora Honey Samples Collected from Three Regions in East Libya

Nagwa H. S. Ahmida; Najma H. Towier; Seham Shaboun; Salwa Y. S. Rahil; Aziza Ahmida; Randa. S. El-zwaeya; Abdelkarem A. Elgazali

Volume 3, Issue 4 , December 2021, , Pages 361-374

https://doi.org/10.22034/ajcb.2021.316305.1099

Abstract
  Honey is used for nutritional, therapeutic and manufacturing purposes and it is a significant product in the global market. Honey is defending as a natural indicator of floral biodiversity ...  Read More
Evaluation of Metal Composition of Cast Iron Disc Used in Local Grinding Machine
Evaluation of Metal Composition of Cast Iron Disc Used in Local Grinding Machine

Damilola Christana Petinrin; Adeyemi S. Adebisi; Olugbenga O. Oluwasina

Volume 3, Issue 4 , December 2021, , Pages 375-383

https://doi.org/10.22034/ajcb.2021.302543.1095

Abstract
  The need to prevent metal-related sickness is the driving force for this research. The research evaluates the composition and concentration of metals present in cast iron grinding disc ...  Read More
Syntheses, Characterization and Biological Evaluation of Some New (2E)-1-(4'-bromophenyl)-3-(4-(diphenylamino)phenyl)prop-2-en-1-one Chalcones and their analogues
Syntheses, Characterization and Biological Evaluation of Some New (2E)-1-(4'-bromophenyl)-3-(4-(diphenylamino)phenyl)prop-2-en-1-one Chalcones and their analogues

Abdulrazaq Tukur; James Dama Habila; Rachael Gbekele-Oluwa Ayo; Ogunkemi Risikat Agbeke Iyun

Volume 3, Issue 4 , December 2021, , Pages 384-397

https://doi.org/10.22034/ajcb.2021.320216.1103

Abstract
  Eight novel triphenylamine chalcones with different substitution patterns were successfully synthesized using the conventional Claisen-Schmidt condensation reaction in basic medium ...  Read More
Determination of Mercury Contents in Some Commercially Available Skin-Lightening Creams in Benghazi-Libya Markets
Determination of Mercury Contents in Some Commercially Available Skin-Lightening Creams in Benghazi-Libya Markets

Nagwa H. S. Ahmida; Aziza Ahmida; Sami. H. Almabrok; N. H. Towier; Randa. S. El-zwaeya; Salah A Gadallaa

Volume 3, Issue 3 , August 2021, , Pages 209-217

https://doi.org/10.22034/ajcb.2021.286365.1082

Abstract
  Mercury and its compounds are well known to have toxic effects on human body. Many research studies have reported in this field. These studies found that the prolong using of the skin ...  Read More
Comparison of the phytochemical composition of Euclea divinorum Hern (Ebenaceae) leaves, tender stems and root bark
Comparison of the phytochemical composition of Euclea divinorum Hern (Ebenaceae) leaves, tender stems and root bark

Immaculate Mbabazi; Phanice Wangila; Isaac O. K’Owino

Volume 3, Issue 3 , August 2021, , Pages 218-242

https://doi.org/10.22034/ajcb.2021.289661.1083

Abstract
  Euclea divinorum Hern (Ebenaceae) has a long history of folkloric use in the treatment of different diseases. However, there are few reports on the responsible phytochemicals in its ...  Read More
Chemical and Biological potentials of semicarbazide and thiosemicarbazide derivatives and their metals complexes
Chemical and Biological potentials of semicarbazide and thiosemicarbazide derivatives and their metals complexes

Mohammad Asif; Saad Alghamdia

Volume 3, Issue 3 , August 2021, , Pages 243-270

https://doi.org/10.22034/ajcb.2021.294269.1086

Abstract
  Organic compounds have plays vital role in biological chemical activities and also use for increase people's quality of life. Semicarbazide and thiosemicarbazide are sulfur and nitrogen-containing ...  Read More
Curcumin – A promising phytocompound of immense potential
Curcumin – A promising phytocompound of immense potential

Mehrukh Zehravi; Mudasir Maqbool; Irfat Ara

Volume 3, Issue 3 , August 2021, , Pages 271-276

https://doi.org/10.22034/ajcb.2021.295567.1088

Abstract
  Curcumin is a polyphenol derived from the Curcuma longa plant (diferuloylmethane). For thousands of years it has been employed in Ayurvedic medicine for a range of therapeutic features, ...  Read More
Utilization of Herbal Cosmetics: A brief overview
Utilization of Herbal Cosmetics: A brief overview

Rabiah Bashir; Mudasir Maqbool; Mehrukh Zehravi; Irfat Ara

Volume 3, Issue 3 , August 2021, , Pages 277-288

https://doi.org/10.22034/ajcb.2021.297472.1090

Abstract
  The role of Indian herbs in herbal cosmetics is well-known throughout the world. Beauty and makeup are as old as humanity and society itself. As a result, women with herbs use various ...  Read More
Herbs Boosting Immunity in Covid-19: An Overview
Herbs Boosting Immunity in Covid-19: An Overview

Irfat Ara; Mudasir Maqbool; Mehrukh Zehravi; Imran Gani

Volume 3, Issue 3 , August 2021, , Pages 289-294

https://doi.org/10.22034/ajcb.2021.299322.1091

Abstract
  In the current situation, it is more crucial than ever to strengthen our defence system against it, as no evidence-based treatment for COVID-19 has been developed. Traditional spices ...  Read More
Theoretical Studies of 1, 2, 3-Triazole and Isoxazole-Linked Pyrazole Hybrids as Antibacterial Agents: An Approach of Docking and Density Functional Theory
Theoretical Studies of 1, 2, 3-Triazole and Isoxazole-Linked Pyrazole Hybrids as Antibacterial Agents: An Approach of Docking and Density Functional Theory

Afeez B Adegoke; Gafar Olatunji Azeez; Ajerogba Lawal; Musa Olalekan Imran

Volume 3, Issue 2 , May 2021, , Pages 148-159

https://doi.org/10.22034/ajcb.2021.265760.1075

Abstract
  Inhibitory activities of five derivatives of 1,2,3-triazole and isoxazole-linked pyrazole hybrids (A,B,C,D and D) were investigated on two bacteria cell lines E.coli (5R1R) and S.aureous ...  Read More
Mechanistic Investigation of Formation of Some Pharmacological Active Beta-Diketo Compounds and Related Nitrogen Heterocycles
Mechanistic Investigation of Formation of Some Pharmacological Active Beta-Diketo Compounds and Related Nitrogen Heterocycles

Noor ud Din Zargar; Khaliq uz Zaman Khan

Volume 3, Issue 2 , May 2021, , Pages 160-175

https://doi.org/10.22034/ajcb.2021.258161.1070

Abstract
  Beta-diketo compounds and related N-heterocycles have played a significant role in synthetic organic chemistry. A multistep mechanism for a catalyze base reaction of 1,3-indandione ...  Read More
Copper-Catalyzed Decarboxylation of Α,Β-Unsaturated Carboxylic Acids with N-Fluorobenzenesulfonimide: Synthesis of Enamines
Copper-Catalyzed Decarboxylation of Α,Β-Unsaturated Carboxylic Acids with N-Fluorobenzenesulfonimide: Synthesis of Enamines

Tony Wheellyam Pouambeka; Guy Crepin Enoua; Feueltgaldah Christian Bopoundza; Hubert Makomo; Bob Wilfrid Loumouamou; Qian Zhan

Volume 3, Issue 2 , May 2021, , Pages 176-187

https://doi.org/10.22034/ajcb.2021.258199.1071

Abstract
  A highly efficient and easy protocol Copper-catalyzed decarboxylative amination of α,β-unsaturated carboxylic acids with N-Fluorobenzenesulfonimide as a nitrogen source and ...  Read More