Substitution of Carbonyl Group of Ellagic Acid with Silanediol Group for Better Inhibition of VEGFR-2 Kinase Enzyme
1. Substitution of Carbonyl Group of Ellagic Acid with Silanediol Group for Better Inhibition of VEGFR-2 Kinase Enzyme

Mehdi Nabati; Elham Pournamdari; Vida Bodaghi-Namileh; Yahya Dashti-Rahmatabadi; Saman Sarshar

Volume 2, Issue 2 , Spring 2020, , Pages 64-72

http://dx.doi.org/10.33945/SAMI/AJCB.2020.2.5

Abstract
  Evaluating structural and medicinal properties of novel silicon containing molecules of Ellagic acid (EADC) is the main purpose of this work. Density functional theory (DFT) methods ...  Read More
Favipiravir: Structural Analysis and Activity against COVID-19
2. Favipiravir: Structural Analysis and Activity against COVID-19

Kun Harismah; Mahmoud Mirzaei

Volume 2, Issue 2 , Spring 2020, , Pages 55-60

http://dx.doi.org/10.33945/SAMI/AJCB.2020.2.3

Abstract
  Within this work, we have performed an in silico research for structural analysis of Favipiravir and its activity against COVID-19. To this aim, tautomers formations of Favipiravir ...  Read More
Withaferin A (WIT) Interaction with beta–Tubulin to Promote Tubulin Degradation: In Silico Study
3. Withaferin A (WIT) Interaction with beta–Tubulin to Promote Tubulin Degradation: In Silico Study

Mehdi Nabati; Elham Pournamdari; Yahya Dashti-Rahmatabadi; Saman Sarshar

Volume 2, Issue 1 , Winter 2020, , Pages 26-32

http://dx.doi.org/10.33945/SAMI/AJCB.2020.1.5

Abstract
  The main purpose of present study is evaluation of structural and medicinal properties for Withaferin A (WIT) using density functional theory (DFT) method. All studies are done via ...  Read More
Antidepressant Activity of Curcumin by Monoamine Oxidase–A Inhibition
4. Antidepressant Activity of Curcumin by Monoamine Oxidase–A Inhibition

Hamidreza Nazemi; Mahmoud Mirzaei; Elham Jafari

Volume 1, Issue 1 , Autumn 2019, , Pages 3-9

http://dx.doi.org/10.33945/SAMI/AJCB.2019.1.2

Abstract
  Antidepressant activity of curcumin (Cur), as a very well–known herbal product, has been investigated within this work. Two tautomeric forms of Cur–a and Cur–b in ...  Read More
Flavonoid Derivatives for Monoamine Oxidase–A Inhibition
5. Flavonoid Derivatives for Monoamine Oxidase–A Inhibition

Arman N. Esfahani; Mahmoud Mirzaei

Volume 1, Issue 1 , Autumn 2019, , Pages 17-22

http://dx.doi.org/10.33945/SAMI/AJCB.2019.1.4

Abstract
  The in silico molecular docking (MD) simulations have been performed to examine the efficacy of three flavonoid ligands including chrysin, apigenin and luteolin on monoamine oxidase–A ...  Read More