Pearl Rhea Fernandes; Ashwini . Madnala; Nisha . Donde; Amit Anil Pawar; Maryappa C. Sonawale
Abstract
Baclofen is a Gamma Amino Butyric acid (GABA) agonist to relax skeletal muscles. It is especially effective in treating muscular spasticity. In this research, we now describe the ...
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Baclofen is a Gamma Amino Butyric acid (GABA) agonist to relax skeletal muscles. It is especially effective in treating muscular spasticity. In this research, we now describe the synthesis of Baclofen using a new approach which begins with 4- chlorobenzaldehyde. We have carried all reactions by the green method. It gives the better yield. The identity of this product was confirmed by spectral analysis and compared with the standard Baclofen. New and eco-friendly approach was developed for the synthesis